Anchoring Local Translation in Neurons
نویسنده
چکیده
In probing how protein synthesis in neurons is coupled to extracellular stimuli, Tcherkezian et al. (2010) discover that the receptor protein DCC anchors components of the translation machinery at the plasma membrane. Binding of DCC to its ligand, netrin, triggers the release of these components to initiate spatially restricted protein synthesis.
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عنوان ژورنال:
- Cell
دوره 141 شماره
صفحات -
تاریخ انتشار 2010